Serya, Rabah A.T.: search on Z-Library

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1

Identification of new pyrrolo[2,3-d]pyrimidines as potent VEGFR-2 tyrosine kinase inhibitors: Design, synthesis, biological evaluation and molecular modeling

Adel, Mai, Serya, Rabah A.T., Lasheen, Deena S., Abouzid, Khaled A.M.

Journal:

Bioorganic Chemistry

Year:

2018

Language:

english

File:

PDF, 2.40 MB

english, 2018

2

Design, synthesis, biological evaluation and dynamics simulation of indazole derivatives with antiangiogenic and antiproliferative anticancer activity

Elsayed, Nevine M.Y., Serya, Rabah A.T., Tolba, Mai F., Ahmed, Marawan, Barakat, Khaled, Abou El Ella, Dalal A., Abouzid, Khaled A.M.

Journal:

Bioorganic Chemistry

Year:

2019

Language:

english

File:

PDF, 4.84 MB

english, 2019

3

Penicillin binding protein 2a: An overview and a medicinal chemistry perspective

Shalaby, Menna-Allah W., Dokla, Eman M.E., Serya, Rabah.A.T., Abouzid, Khaled A.M.

Journal:

European Journal of Medicinal Chemistry

Year:

2020

File:

PDF, 6.16 MB

2020

4

Molecular design and synthesis of 1,4-disubstituted piperazines as α1-adrenergic receptor blockers

Abou El-Ella, Dalal A., Hussein, Mohammed M., Serya, Rabah A.T., Abdel Naby, Rana M., Al-Abd, Ahmed M., Saleh, Dalia O., El-Eraky, Wafaa I., Abouzid, Khaled A.M.

Journal:

Bioorganic Chemistry

Year:

2014

Language:

english

File:

PDF, 946 KB

english, 2014

5

Synthesis, ADMET properties, and biological evaluation of benzothiazole compounds targeting CXCR2

Mehanna, Wesam E., Lu, Tiangong, Debnath, Bikash, Lasheen, Deena S., Serya, Rabah A. T., Abouzid, Khaled A., Neamati, Nouri

Journal:

Year:

2017

Language:

english

File:

PDF, 2.26 MB

english, 2017

6

How to train your inhibitor: Design strategies to overcome resistance to Epidermal Growth Factor Receptor inhibitors

Milik, Sandra N., Lasheen, Deena S., Serya, Rabah A.T., Abouzid, Khaled A.M.

Journal:

European Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 9.15 MB

english, 2017

7

Design, synthesis and biological evaluation of indazole–pyrimidine based derivatives as anticancer agents with anti-angiogenic and antiproliferative activities

Elsayed, Nevine M. Y., Abou El Ella, Dalal A., Serya, Rabah A. T., Tolba, Mai F., Shalaby, Raed, Abouzid, Khaled A. M.

Journal:

Year:

2016

Language:

english

File:

PDF, 2.98 MB

english, 2016

8

Rational design, synthesis and 2D-QSAR studies of antiproliferative tropane-based compounds

Ismail, Nasser S. M., George, Riham F., Serya, Rabah A. T., Baselious, Fady N., El-Manawaty, May, Shalaby, ElSayed M., Girgis, Adel S.

Journal:

Year:

2016

Language:

english

File:

PDF, 666 KB

english, 2016

9

Fragment-Based Drug Discovery in the Bromodomain and Extra-Terminal Domain Family

Radwan, Mostafa, Serya, Rabah

Journal:

Archiv der Pharmazie

Year:

2017

Language:

english

File:

PDF, 1.95 MB

english, 2017

10

Synthesis and in vitro antiproliferative activity of novel pyrazolo[3,4-d]pyrimidine derivatives

Abdou, Nermin S., Serya, Rabah A. T., Esmat, Ahmed, Tolba, Mai F., Ismail, Nasser S. M., Abouzid, Khaled A. M.

Journal:

Year:

2015

Language:

english

File:

PDF, 2.68 MB

english, 2015

11

Anti-acetylcholinesterase activity of essential oils and their major constituents from four Ocimum species

Farag, Mohamed A., Ezzat, Shahira M., Salama, Maha M., Tadros, Mariane G., Serya, Rabah A.T.

Journal:

Zeitschrift für Naturforschung C

Year:

2016

Language:

english

File:

PDF, 286 KB

english, 2016

12

Pyrrolopyrimidine, A Multifaceted Scaffold in Cancer Targeted Therapy

Adel, Mai, Serya, Rabah, Lasheen, Deena, Abouzid, Khaled

Journal:

Year:

2018

Language:

english

File:

PDF, 765 KB

english, 2018

13

Targeting apoptotic machinery as approach for anticancer therapy: Smac mimetics as anticancer agents

Elsayed, Nevine M.Y., Abou El Ella, Dalal A., Serya, Rabah A.T., Abouzid, Khaled A.M.

Journal:

Future Journal of Pharmaceutical Sciences

Year:

2015

Language:

english

File:

PDF, 907 KB

english, 2015

14

Design, Synthesis and Biological Evaluation of Novel Quinazoline-Based Anti-inflammatory Agents Acting as PDE4B Inhibitors

Serya, Rabah Ahmed Taha, Abbas, Abeer Hussin, Ismail, Nasser Saad Mohamed, Esmat, Ahmed, Abou El Ella, Dalal Abdelrahman

Year:

2015

Language:

english

File:

PDF, 3.33 MB

english, 2015

15

Pyrazolo[3,4-d]pyrimidine based scaffold derivatives targeting kinases as anticancer agents

Ismail, Nasser S.M., Ali, Eslam M.H., Ibrahim, Diaa A., Serya, Rabah A.T., Abou El Ella, Dalal. A.

Journal:

Future Journal of Pharmaceutical Sciences

Year:

2016

Language:

english

File:

PDF, 911 KB

english, 2016

16

Click and Release: SO 2 Prodrugs with Tunable Release Rates

Ji, Xingyue, El-labbad, Eman M., Ji, Kaili, Lasheen, Deena S., Serya, Rabah A. T., Abouzid, Khaled A., Wang, Binghe

Journal:

Organic Letters

Year:

2017

Language:

english

File:

PDF, 821 KB

english, 2017

17

Alkoxyphenylthiazoles with broad-spectrum activity against multidrug-resistant gram-positive bacterial pathogens

ElAwamy, Moustafa, Mohammad, Haroon, Hussien, Abdelrahman, Abutaleb, Nader S., Hagras, Mohamed, Serya, Rabah A.T., Taher, Azza T., Abouzid, Khaled AM, Seleem, Mohamed N., Mayhoub, Abdelrahman S.

Journal:

European Journal of Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 803 KB

english, 2018

18

Surmounting the resistance against EGFR inhibitors through the development of thieno[2,3- d ]pyrimidine-based dual EGFR/HER2 inhibitors

Milik, Sandra N., Abdel-Aziz, Amal Kamal, Lasheen, Deena S., Serya, Rabah A.T., Minucci, Saverio, Abouzid, Khaled A.M.

Journal:

European Journal of Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 3.01 MB

english, 2018

19

Design, synthesis, 3D pharmacophore, QSAR, and docking studies of carboxylic acid derivatives as Histone Deacetylase inhibitors and cytotoxic agents

Abdel-Atty, Mona M., Farag, Nahla A., Kassab, Shaymaa E., Serya, Rabah A.T., Abouzid, Khaled A.M.

Journal:

Bioorganic Chemistry

Year:

2014

Language:

english

File:

PDF, 1.06 MB

english, 2014

20

Pyridazine Based Scaffolds as Privileged Structures in anti-Cancer Therapy

Jaballah, Maiy, Serya, Rabah, Abouzid, Khaled

Journal:

Year:

2017

Language:

english

File:

PDF, 858 KB

english, 2017

21

Synthesis and molecular docking studies of some novel Schiff bases incorporating 6-butylquinolinedione moiety as potential topoisomerase IIβ inhibitors

Hassanin, Hany M., Serya, Rabah A. T., Abd Elmoneam, Wafaa R., Mostafa, Mai A.

Journal:

Royal Society Open Science

Year:

2018

Language:

english

File:

PDF, 2.12 MB

english, 2018

22

Design, synthesis and molecular docking of novel pyrazolo[1,5-a][1,3,5]triazine derivatives as CDK2 inhibitors

Oudah, Khulood H., Najm, Mazin A.A., Samir, Nermin, Serya, Rabah A.T., Abouzid, Khaled A.M

Journal:

Bioorganic Chemistry

Year:

2019

Language:

english

File:

PDF, 3.24 MB

english, 2019

23

Structure-based design and synthesis of novel pseudosaccharine derivatives as antiproliferative agents and kinase inhibitors

Elsayed, Mohamed S.A., El-Araby, Moustafa E., Serya, Rabah A.T., El-Khatib, Ahmed H., Linscheid, Michael W., Abouzid, Khaled A.M.

Journal:

European Journal of Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 765 KB

english, 2013

24

Towards discovery of novel scaffold with potent antiangiogenic activity; design, synthesis of pyridazine based compounds, impact of hinge interaction, and accessibility of their bioactive conformation on VEGFR-2 activities

Jaballah, Maiy Y., Serya, Rabah A. T., Saad, Nasser, Khojah, Sohair M., Ahmed, Marawan, Barakat, Khaled, Abouzid, Khaled A. M.

Journal:

Journal of Enzyme Inhibition and Medicinal Chemistry

Year:

2019

File:

PDF, 2.20 MB

2019

25

Novel quinoline-3-carboxamides (Part 2): Design, optimization and synthesis of quinoline based scaffold as EGFR inhibitors with potent anticancer activity

Aly, Rasha M., Serya, Rabah A.T., El-Motwally, Amira M., Esmat, Ahmed, Abbas, Safinaz, Abou El Ella, Dalal A.

Journal:

Bioorganic Chemistry

Year:

2017

Language:

english

File:

PDF, 4.19 MB

english, 2017

26

Ligand design and synthesis of new imidazo[5,1-b]quinazoline derivatives as α1-adrenoceptor agonists and antagonists

Mohamed A.H. Ismail, Mohamed N.Y. Aboul-Enein, Khaled A.M. Abouzid, Rabah A.T. Serya

Journal:

Bioorganic & Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 492 KB

english, 2006

27

Towards discovery of novel scaffold with potent antiangiogenic activity; design, synthesis of pyridazine based compounds, impact of hinge interaction, and accessibility of their bioactive conformation on VEGFR-2 activities

Jaballah, Maiy Y., Serya, Rabah A. T., Saad, Nasser, Khojah, Sohair M., Ahmed, Marawan, Barakat, Khaled, Abouzid, Khaled A. M.

Journal:

Journal of Enzyme Inhibition and Medicinal Chemistry

Year:

2019

Language:

english

File:

PDF, 2.20 MB

english, 2019

28

Development of Potent Adenosine Monophosphate Activated Protein Kinase (AMPK) Activators

Dokla, Eman M. E., Fang, Chun-Sheng, Lai, Po-Ting, Kulp, Samuel K., Serya, Rabah A. T., Ismail, Nasser S. M., Abouzid, Khaled A. M., Chen, Ching-Shih

Journal:

Year:

2015

Language:

english

File:

PDF, 2.44 MB

english, 2015

29

Furo[2,3-d]pyrimidine based derivatives as kinase inhibitors and anticancer agents

Aziz, Marwa A., Serya, Rabah A.T., Lasheen, Deena S., Abouzid, Khaled A.M.

Journal:

Future Journal of Pharmaceutical Sciences

Year:

2016

Language:

english

File:

PDF, 841 KB

english, 2016

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